refractory
not responding to treatment or difficult to manage
The patient's refractory pain required multiple rounds of treatment before any relief was achieved.
Set 192 · Study 1 / 5
Exitnot responding to treatment or difficult to manage
The patient's refractory pain required multiple rounds of treatment before any relief was achieved.
Set 192 of GRE Vocabulary covers 5 words: refractory, saturnine, sedulous, shrill, sordid. Each entry below includes its definition, an example sentence, and synonyms — practice them with the interactive cards above.
not responding to treatment or difficult to manage
The patient's refractory pain required multiple rounds of treatment before any relief was achieved.
gloomy or moody in temperament
Despite his saturnine demeanor, he surprised everyone with a rare smile during the celebration.
showing dedication and diligence in one’s work or tasks
Her sedulous efforts in completing the project ahead of schedule did not go unnoticed by her supervisor.
having a high-pitched and piercing sound
The shrill sound of the whistle pierced through the noise of the crowd, grabbing everyone's attention.
involving ignoble actions and motives; arousing moral distaste and contempt
The investigation uncovered a sordid tale of corruption and deceit involving city officials.